WebNov 1, 2011 · DHX9 interacted with IPS-1 via the HelicC-HA2-DUF and CARD domains of DHX9 and IPS-1, respectively. Knockdown of DHX9 expression in mDCs blocked the activation of NF-κB and IFN regulatory factor 3 by dsRNA. Collectively, these results suggest that DHX9 is an important RNA sensor that is dependent on IPS-1 to sense … WebMar 21, 2024 · DHX29 (DExH-Box Helicase 29) is a Protein Coding gene. Diseases associated with DHX29 include Chromosome 22Q11.2 Deletion Syndrome, Distal.Among its related pathways are Translational Control and VEGFA-VEGFR2 signaling pathway.Gene Ontology (GO) annotations related to this gene include nucleic acid binding and helicase …
The helicase protein DHX29 promotes translation initiation, cell ...
WebDec 29, 2009 · Down-regulation of DHX29 leads to impaired translation, resulting in disassembly of polysomes and accumulation of mRNA-free 80S monomers. DHX29 depletion also impedes cancer cell growth in culture and in xenografts. Thus, DHX29 is a bona fide translation initiation factor that potentially can be exploited as a target to inhibit … WebOct 9, 2012 · The importance of DHX29 for translation is underlined by observations that silencing its expression in human cells led to a general impairment of translation, particularly of mRNAs with long, structured 5′ … early voting in texas for november
Helicase proteins DHX29 and RIG-I cosense cytosolic nucleic acids in ...
WebAmong them, DHX29 was identi- fied as a positive regulator of intracellular HMW Poly(I:C)-induced IFN-β-Luc reporter activity as well as interferon-stimulate d response element … WebMay 12, 2014 · The cytosolic nucleic acid sensing by DHX29 in human epithelial cells and fibroblasts is independent of stimulator of interferon genes but is dependent on retinoic acid-inducible gene 1 (RIG-I) and mitochondrial antiviral signaling protein (MAVS). WebMar 21, 2024 · DHX29 (DExH-Box Helicase 29) is a Protein Coding gene. Diseases associated with DHX29 include Chromosome 22Q11.2 Deletion Syndrome, Distal. … csumb student housing