Granulophysin
WebJun 1, 1994 · Abstract. Granulophysin, a protein described in platelet dense granule membranes, has been shown to be similar or identical to CD63, a lysosomal … WebCD63 was first described in granules of resting platelets and on the surface membrane on activated platelets. CD63 was later identified as granulophysin, a platelet dense granule glycoprotein. The molecular …
Granulophysin
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WebNormal human peripheral blood cells were stained with CD193 (CCR3) Monoclonal Antibody, PE (Product # 12-1939-42) and IgE Monoclonal Antibody, FITC (Product # 11-6986-42) only (blue histogram), or stained with CD63 Monoclonal Antibody, NovaFluor Red 700 (Product # H074T03R03) (purple histogram). WebJun 15, 2000 · Arrowheads indicate granulophysin (10-nm gold particles), and arrows indicate α-granule marker von Willebrand factor (5-nm gold particles). Both proteins can be found within the same MVB, but they are segregated from each other in distinct microvesicles. Granulophysin is also preferentially associated with the limiting …
WebCD63 molecule. Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and ... WebNov 6, 2024 · Level of granulophysin on the platelet surface. A, 5‐ HT /catecholamine‐treated or ‐untreated platelets were evaluated by measuring the level of granulophysin, a surrogate marker for dense‐granule …
Web2024 CiteAb Awards - View the winners now! ... Search WebApr 1, 1993 · The levels and expression of the proteins CD63 and granulophysin in platelets from control and from a Hermansky-Pudlak syndrome subject (a condition characterized by dense granule and lysosomal deficiencies and the accumulation of ceroid-like material in reticuloendothelial cells) were examined. Immunofluorescence studies …
WebThese characteristics are similar to an individual with Hermansky-Pudlak syndrome and are consistent with a platelet dense granule deficiency. In contrast, immunofluorescence studies using an antibody against the dense granule membrane protein granulophysin suggested that both sisters had numbers of granules within the normal range.
WebGenerally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. Shipping. This product is provided as lyophilized powder which is shipped with ice packs. sand art bottles michaelsWebNaked mole-rats are long-lived animals that show unusual resistance to hypoxia, cancer and ageing. Protein deimination is an irreversible post-translational modification caused by the peptidylarginine deiminase (PAD) family of enzymes, which convert arginine into citrulline in target proteins. Protein deimination can cause structural and functional protein changes, … sand art bottles wholesaleWebGranulophysin (CD63) is a protein in the tetraspanin group and is found in, among others, the dense granules and the α-granules of platelets [139,140], as well as the azurophilic granules of ... sand art brownies taste of homeWebJul 1, 1992 · We recently reported the characterization of a platelet granule membrane protein of molecular weight (mol wt) 40,000 called granulophysin (Gerrard et al: Blood … sandartbysubby.comWebGranulopoiesis and Monocytopoiesis (Myelopoiesis). Granulopoiesis is the production of neutrophils, eosinophils, and basophils, whereas monocyte production is termed … sand art brownies recipeWebDescription: Homo sapiens CD63 molecule (CD63), transcript variant 3, mRNA. (from RefSeq NM_001257389) RefSeq Summary (NM_001257389): The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the … sand art cape townWebnoun. gran· u· lo· poi· e· sis - (ˌ)lō-ˌpȯi-ˈē-səs. plural granulopoieses -ˌsēz. : the formation of blood granulocytes typically in the bone marrow. called also granulocytopoiesis. … sand art captain haddock